Towards a Functional Cure for Hbv: Exploiting Lessons From HBV-Hiv Co-Infection

Abstract

Hepatitis B virus (HBV) infection can be treated, but therapy is usually lifelong and has side effects, so a cure for HBV is very important. We work closely with colleagues in Asia where both HBV and HIV are common so this provides a unique opportunity to study HBV. We will investigate how an effective immune response against the 2 main HBV proteins is developed. If we can understand how the immune response works against HBV, this could be used to develop new therapies to develop a cure for HBV

Related publications (1)

Kinetics and Predictors of Hepatitis B Surface Antigen Loss After Commencing Hepatitis B Virus (HBV)–Active Antiretroviral Therapy in the Setting of HIV and Chronic HBV Coinfection

J Audsley, A Avihingsanon, X Li, R Edwards, K Jackson, N Warner, O Maslac, PA Revill, HMS Lwin, S Gatechompol, N Kumarasamy, T Spelman, I Azwa, A Kamarulzaman, SR Lewin, J Sasadeusz

2026-01-15

Background. An effective therapeutic strategy for hepatis B virus (HBV) cure remains an urgent unmet need. We aimed to define the ..